Multivessel Coronary Artery Disease in Diabetes Mellitus Patients

Abstract views: 1119 / PDF downloads: 714


  • Amanj Kamal Mohammed Thoracic and Cardiovascular Surgery Department, School of Medicine, University of Sulaimani, Sulaimani, Iraq


Coronary artery disease is the most common cardiac disease with a worldwide distribution, and it is responsible for most of the mortalities regarding cardiovascular diseases if not detected early and treated properly. There are many lines in the treatment of coronary artery disease, starting from medical therapy, percutaneous coronary intervention, and coronary artery bypass graft surgery, preference of the choice of the type of the treatment depends on many factors. In fact when coronary artery bypass graft is indicated, although it carries a considerable risk of surgery, but the long-term survival is notably better than the other ways of treatment. This study was done to determine that the prevalence of multivessel coronary artery disease is more in diabetic patients than non-diabetic patients. And more in females than males. In this study hundred, ninety patients were retrospectively studied, all of them underwent coronary artery bypass graft surgery with or without other concomitant cardiac procedures (like valve surgery), but most of them were coronary artery bypass graft alone. We found that the number of coronary arteries affected is strongly related to the presence of diabetes mellitus. And females are more prone to have coronary artery disease than males. Thus diabetes mellitus is the most common risk factor for the development of cardiovascular disease, and the severity of the condition is confirmed by the number of the coronary arteries involved as well as the calcification or multiple stenosis in the same vessel.


cardiac surgery, coronary artery bypass graft surgery, diabetes mellitus, multivessel coronary artery disease.


[1] S. Pant, A. Deshmukh, G. S. Gurumurthy , J. L. Mehta, N. V. Pothineni, F. Romeo and T. E. Watts, "Inflammation and atherosclerosis--revisited," J Cardiovasc Pharmacol Ther, vol. 19, no. 2, pp. 170-178, 2014.
[2] K. Yahagi, F. D. Kolodgie, C. Lutter, H. Hori, M. E. Romero, A. V. Finn and R. Virmani, "Pathology of Human Coronary and Carotid Artery Atherosclerosis and Vascular Calcification in Diabetes Mellitus," Arterioscler Thromb Vasc Biol, vol. 37, no. 2, pp. 191-204, 2017.
[3] D. Aronson and E. R. Edelman, "Coronary artery disease and diabetes mellitus," Cardiol Clin, vol. 32, no. 3, pp. 439-455, 2014.
[4] R. Naito and K. Miyauchi, "Coronary Artery Disease and Type 2 Diabetes Mellitus," Int Heart J, vol. 58, no. 4, pp. 475-480, 2017.
[5] N. Agrawal, "Superdominant left-circumflex artery supplying significant proportion of RCA and LAD territory," BMJ Case Reports, 2015.
[6] D. P. Taggart, "CABG in 2012: Evidence, practice and the evolution of guidelines," Glob Cardiol Sci Pract. , vol. 2012, no. 2, pp. 21-28, 2012.
[7] S. J. Head, P. M. Davierwala, S. R. Redwood , A. Colombo, M. J. Mack, M. C. Morice, D. R. Holmer Jr, T. E. Feldman, E. Ståhle, P. Underwood, K. D. Dawkins, A. P. Kappetein and F. W. Mohr, "Coronary artery bypass grafting vs. percutaneous coronary intervention for patients with three-vessel disease: final five-year follow-up of the SYNTAX trial," Eur Heart J, vol. 35, no. 40, pp. 2821-30, 2014.
[8] A. A. Laverty, A. Bottle, S. H. Kum, B. Visani, A. Majeed, C. Millett and E. P. Vamos, "Gender differences in hospital admissions for major cardiovascular events and procedures in people with and without diabetes in England: a nationwide study 2004-2014.," Cardiocasc Diabetol, vol. 16, no. 1, p. 100, 2017.
[9] T Christus, A. M. Shukkur, I. Rashdan, T. Koshy, M. Alanbaei, M. Zubaid, N. Hayat and A Alsayegh, "Coronary Artery Disease in Patients Aged 35 or less - A Different Beast?," Heart Views, vol. 12, no. 1, pp. 7-11, 2011.
[10] E. Pietrzyk, K. Michta, I. Gorcyca-Michta and B. Wo?akowska-Kap?on, "Coronary artery bypass grafting in patients over 80 years of age: a single-centre experience," Kardiol Pol, vol. 72, no. 7, pp. 598-603, 2014.
[11] P. Vladan, J. M. Snežana, P. Dejan and R. Dragisa, "Quality of Life in Patients of Different Age Groups before and after Coronary Artery By-Pass Surgery," Ann Thorac Cardiovasc Surg, vol. 21, no. 5, pp. 474-480, 2015.
[12] G. S. Gudnadottir, K. Andersen, I. S. Thrainsdottir, S. K. James, B. Lagerqvist and T. Gudnason, "Gender differences in coronary angiography, subsequent interventions, and outcomes among patients with acute coronary syndromes," Am Heart J, vol. 191, pp. 65-74, 2017.
[13] M. A. Isorni, D. Blanchard, N. Teixeira, H. le Breton and N. Renault , "Impact of gender on use of revascularization in acute coronary syndromes: the national observational study of diagnostic and interventional cardiac catheterization (ONACI)," Catheter Cardiovasc Interv, vol. 86, no. 2, pp. 58-65, 2015.
[14] L. C. Godoy, V. Rao and M. E. Farkouh, "Diabetes and multivessel disease: coronary artery bypass grafting remains king," Curr Opin Cardiol, vol. 33, no. 5, pp. 551-557, 2018.
[15] S. N. Burgess, C. J. Mussap and J. K. French, "Management of acute coronary syndromes in patients with diabetes: implications of the FREEDOM trial," Clin Ther, vol. 35, no. 8, pp. 1069-75, 2013.


How to Cite

A. K. Mohammed, “Multivessel Coronary Artery Disease in Diabetes Mellitus Patients”, KJAR, vol. 4, no. 2, pp. 121–127, Nov. 2019, doi: 10.24017/science.2019.2.12.

Article Metrics





Pure and Applied Science