Formulation, Phytochemical Characterization, and Clinical Assessment of a Novel Natural Supplement Targeting Body Composition in Physically Active Individuals: A Randomized Clinical Trial

Tablo Azad Hama salih; Halgord Ali M. Farag

doi:10.24017/science.2025.2.2

Authors

Tablo Azad Hama salih Food Science and Quality Control, Halabja Technical College, Sulaimani Polytechnic University, Sulaymaniyah, Iraq https://orcid.org/0009-0002-5624-5931
Halgord Ali M. Farag Food Science and Quality Control, Halabja Technical College, Sulaimani Polytechnic University, Sulaymaniyah, Iraq https://orcid.org/0000-0002-8284-7541

Abstract

Nutritional supplementation plays a pivotal role in optimizing body composition, recovery, and performance in physically active individuals. This study aimed to evaluate the effects of an 8-week intervention with a novel natural supplement (NNS) on body composition participants. In a randomized, placebo-controlled trial, 55 participants (NNS: n = 28; placebo: n = 27) consumed either the NNS formulation comprising whey and pea protein, oats, flaxseed, spinach, beetroot, and chia or a placebo. Body composition (muscle mass, weight, BMI, fat %), oxygen saturation, and heart rate were measured at baseline and post-intervention. After 8 weeks, The NNS group showed a significant increase in muscle mass by 41.9%, rising from 12.96 kg to 18.41 kg (p = 0.000), while the placebo group only increased from 13.94 kg to 14.44 kg. Body weight in the NNS group decreased by 8.14 kg, from 76.54 kg to 68.40 kg (p < 0.001), whereas the placebo group gained 2.46 kg. BMI improved in the NNS group, dropping from 30.98 kg/m² to 25.7 kg/m² (p < 0.001), while remaining stable in the placebo group. Oxygen saturation increased from 95.85% to 98.62% (p = 0.001), and heart rate decreased from 76.00 bpm to 68.22 bpm (p = 0.004) in the NNS group. Fat percentage decreased from 30.63% to 27.11% (p = 0.0297). In conclusion, the novel natural multi-ingredient supplement significantly improved muscle mass, reduced body weight and BMI, and enhanced cardiopulmonary parameters, indicating its potential as a safe and effective nutritional strategy for improving body composition and performance in physically active individuals.

Keywords:

Natural Gym Nutrient, Chemical Profiling, Clinical Assessment, Body Composition, Herbal Formulation

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