Biochemical markers and fertility rate of hydatid cyst isolated from human and animal in Sulaimani province
https://doi.org/10.24017/science.2017.2.2
Abstract views: 1081 / PDF downloads: 798Abstract
Hydatid disease is a helminthic infection, caused by the metacestode stage of cestode belonging to the Echinococcus grnulosus (dog tapeworm). The species and strain identification of Echinococcus are of medical importance for strategic control measuring. The present study achieved to determine and compare fertility and biochemical profiles of hydatid cyst fluid isolated from human, cattle, sheep and goat. The human originated cyst has been found to be more fertile (88%), followed by sheep-originated cyst (85%). The high rate of fertility was found in the liver followed by lungs in all intermediate hosts. However, the statistically significant differences of a biochemical test of cyst fluid among intermediate host were observed just in the uric acid, while the result of biochemical tests Hydatid cyst fluid isolated from liver significantly was higher than that of the lung for the most biochemical tests. The fertility and biochemical parameters value differences directly have related to the location of cyst and strains of E. granulosus. This finding concluded the sheep strain is a predominant strain and responsible for human and animal echinococcosis and sheep is the main intermediate host responsible for the perpetuation of the life cycle of E. granulosus in Sulaimani.
Keywords:
Hydatid cyst, Echinococcus, Biochemical, Fertility, Strain, Cyst fluid.
References
1] J. Eckert, A. M. Gemmell, F. X. Meslin, and Z. Pawlowski, "WHO / OIE manual on Echinococcosis in humans and animals: a public health problem of global concern", Paris: Office International des., Epizooties. pp. 225, 2002.
[2] R. C. A. Thompson, "Biology and systematics of Echinococcus. In Echinococcus and hydatid disease", In: (Thompson, R. C. A. and Lymbery, A. J. (1995). CAB Int. Wallingford, pp.50, 1995.
[3] S. Khademvatan, E. Yousefi, A. Rafiei, M. Rahdar, and J. Saki," Molecular characterization of livestock and human isolates of from south-west Iran", J Helminth. vol. 87, pp. 240-244. 2013.
https://doi.org/10.1017/S0022149X12000296
[4] A. A. Hama, "Epidemiological study and Molecular characterization of E. granulosus, in Kurdistan-Iraq", PhD. Thesis, College of Science, University of Zakho, 2013.
[5] W. M. S. Mero, J. M. S. Jubrael, and A.A. Hama, "Prevalence of hydatid disease among slaughtered animals in Slemani Province/Kurdistan-Iraq", J. UOZ 2, pp. 33-38, 2014.
https://doi.org/10.25271/2014.2.1.125
[6] A.A. Hama, W.M.S. Mero, and J.M.S. Jubrael, "Molecular characterization of E. granulosus, first report of sheep strain in Kurdistan-Iraq" , 2nd International Conference on Ecological, Environmental and Biological Sciences (EEBS™ 2012). Oct. 13-14, Bali, Indonesia., 2012.
[7] WHO, "The control of neglected zoonotic diseases", meeting with the participation of FAO and OIE. Geneva., 2006.
[8] A. R. Satoskar, G. L. Simon, P.J. Hotez, and M. Tsuji, "Medical Parasitology, Landes Bioscience, Texas", pp.320, 2009.
https://doi.org/10.1201/9781498713672
[9] E. K. Markell, D.T. John, and W.A. Krotoski, "Medical Parasitology" 8th ed. W. B. Saunder Company. pp. 253-261, 1999.
[10] K.A. Rood, and J. Kelly, "Prevention of Hydatid Disease", Anim. Health., vol.1,pp. 1-7, 2009.
[11] L. Rinaldi, M.P. Maurelli, F. Capuano, A. G. Perugini, V. Veneziano, and S. Cringoli, "Molecular update and cystic echinococcosis in cattle and water Buffaloes of southern Italy", J. Blackwell Verlag. Zoonosis, public. Health., vol. 55, pp.119-123, 2008.
https://doi.org/10.1111/j.1863-2378.2007.01101.x
[12] L.M. Kumaratilake, and R. C. A. Thompson, "A comparison of Echinococcus granulosus from different geographical areas of Australia using secondary cyst development in mice", Int. J. Parasitol., vol.13, pp.509-515, 1983.
https://doi.org/10.1016/S0020-7519(83)80016-2
[13] A. A. Latif, A. Tanveer, A. Maqbool, N. Siddiqi, M. Kyaw-Tanner, and R. J. Traub, "Morphological and molecular characterization of Echinococcus granulosus in livestock and humans in Punjab, Pakistan", J. Vet. Parasitol., vol.170, pp. 44-49, 2010.
https://doi.org/10.1016/j.vetpar.2010.02.003
[14] E. Sanchez, O. Caceres, C. Naquira, D. Garcia, G. Patino, H. Silvia, A. C. Volotao, and O .Fernandes, "Molecular characterization of Echinococcus granulosus from Peru by sequencing of the mitochondrial cytochrome oxidase subunit 1 gene", Res. Dev. J., 105(6), pp. 806-810, 2010.
https://doi.org/10.1590/S0074-02762010000600013
[15] J. Eckert, M.A. Gemmell, F. X. Meslin, and Z. S. Pawlowski, In: "WHO/OIE Manual on Echinococcosis in Humans and Animals: A Public Health Problem of Global Concern" Paris OIE. pp. 1-265, 2001.
[16] M.F. Harandi, R.P. Hobbs, P.J. Adams, I. Mobedi, U. M. Morgan-Ryan, and R.C.A. Thompson, "Molecular and morphological characterization of Echinococcus granulosus of human and animal origin in Iran." J.Parasitol., 125, pp. 367-373. (2002).
https://doi.org/10.1017/S0031182002002172
[17] A.A. Hama, et al.," A morphologically unusual Echinococcus granulosus (G1 genotype) cyst in a cow from Kurdistan - Iraq" Special Issue: Clinical epidemiology., 5(Special Issue 2), pp.S2-5, 2015.
https://doi.org/10.4172/2161-1165.S2-00
[18] N. Magid, Prevalence of hydatid cyst among slaughter animal in Duhok province, M.Sc. Thesis, College of Veterinary Medicine, Univ. of Duhok. (2008).
[19] A. A. Hama and O. H. Shareef, "Morphological and morphometric study of Echinococcus granulosus ( metacestode ) in Sulaimani Province / Kurdistan", vol. 1, no. 1, pp. 1-6, 2016.
https://doi.org/10.24017/science.2016.1.1.6
[20] A. M. Abdullah, "Epidemiological, Comparative Enzymatic and Total Protein content of hydatid cyst of Ecchinococcus granulosus isolated from Sheep and Goats in Duhok province, Kurdistan Region of Iraq", M.Sc. Thesis, College of Education, Univ.of Duhok, 2010.
[21] H. R. Rahimi, E. B. Kia, S. H. Mirhendi, A. Talebi, H.M. Fasihi, N. Jalali-zand, and M. F. Rokni, " A new primer pair in ITS1 region for molecular studies on Echinococcus granulosus", J. Public, Health., 36 pp. 45-49, 2007.
[22] A. Daryani, R. Alaei, R. Arab, M. Sharif, M. H. Deghahan, and H. Ziaei, "Prevalence of hydatid cyst in slaughtered animals in northwest Iran", J. Anim. and Vet. Adv., vol, 5, no. 4 pp. 330-334, 2006.
[23] B. D. Ahmed, "Molecular Characterization of Echinococcus granulosus Cysts Isolated From Human and Animal Intermediate Hosts in Duhok Province, Kurdistan Region, Iraq", PhD. Thesis, College of Medicine, Univ. of Duhok, Kurdistan Region, Iraq, 2012.
[24] T. Ueno, S. Hirayama, M. Ito, E. Nishioka, Y. Fukushima, T. Satoh, M. Idei, Y. Horiuchi, H. Shoji, H. Ohmura, T. Shimizu, and T. Miida, "Albumin concentration determined by the modified bromocresol purpl method is superior to that by the bromocresol green method for assessing nutritional status in malnourished patients with inflammation", Journal Annals of Clinical Biochemistry, vol. 50 no.6, pp.576-584, 2013. [25] M. Fulks, R. L. Stout, and V. F. Dolan, '"Serum globulin predicts all-cause mortality for life insurance applicants", Journal of Insurance Medicine, vol. 44, pp.93-98, 2014. [26] I .A. Shaafie, A. H. Khan, and K. Rambabu, "Biochemical profiles of hydatid cyst fluids of E. granulosus of human and animal origin in Libya", J. Helminthol. vol.73, pp. 253-258, 1999:
https://doi.org/10.1177/0004563213480137
[27] D. P. Mcmanus, and C. N. L. Macpherson, "Strain characterization in the Hydatid organism, Echinococcus granulosus. Current status and new perspective", Ann. Trop. Med. Parasitol. vol. 78, pp. 193-198, 1984.
https://doi.org/10.1080/00034983.1984.11811799
[28] M. H. Radfar, and N. Iranyar," Biochemical profiles of hydatid cyst fluids of Echinococcus granulosus of human and animal origin in Iran Vet. Arhiv., vol. 74, pp. 435-442, 2004.
[29] Z. I. Hassan, A. A. Meerkhan, B. Boufana, A. A. Hama, B. D. Ahmed, W. M. S. Mero, S. Orsten, M. Interisano, E. Pozio, and A. Casulli, "Two haplotype clusters of Echinococcus granulosus sensu stricto in northern Iraq (Kurdistan region) support the hypothesis of a parasite cradle in the Middle East", Acta Trop., vol. 172, no. April, pp. 201-207, 2017.
https://doi.org/10.1016/j.actatropica.2017.04.028
[30] S. Kamhawi, , and N. Hijjawi, "Current studies on the epidemiology of unilocular hydatidosis in Jordan and its social implication", Report on Parasitic Diseases of the Middle East. National Institutes of Health, Bethesda, Maryland, pp. 8. 1992.
[31] M. Kouidri, F. B. Khoudja, A. Boulkaboul and S. A. Selles "Comparative Study on Fertility, Viability and Biochemical Profiles of Hydatid Cyst Fluid from the Lungs and Liver of Sheep in Algeria", World Applied Sciences Journal 31 vol.10, pp. 1699-1703, 2014.
[32] M. Refik, N. Mehmet, B. Durmaz, and M. E?ri, " Determination of some biochemical parameters in hydatid cyst fluids", Erciyes Tip Derg., vol. 24, no. 1, pp. 10-13, 2002.
[2] R. C. A. Thompson, "Biology and systematics of Echinococcus. In Echinococcus and hydatid disease", In: (Thompson, R. C. A. and Lymbery, A. J. (1995). CAB Int. Wallingford, pp.50, 1995.
[3] S. Khademvatan, E. Yousefi, A. Rafiei, M. Rahdar, and J. Saki," Molecular characterization of livestock and human isolates of from south-west Iran", J Helminth. vol. 87, pp. 240-244. 2013.
https://doi.org/10.1017/S0022149X12000296
[4] A. A. Hama, "Epidemiological study and Molecular characterization of E. granulosus, in Kurdistan-Iraq", PhD. Thesis, College of Science, University of Zakho, 2013.
[5] W. M. S. Mero, J. M. S. Jubrael, and A.A. Hama, "Prevalence of hydatid disease among slaughtered animals in Slemani Province/Kurdistan-Iraq", J. UOZ 2, pp. 33-38, 2014.
https://doi.org/10.25271/2014.2.1.125
[6] A.A. Hama, W.M.S. Mero, and J.M.S. Jubrael, "Molecular characterization of E. granulosus, first report of sheep strain in Kurdistan-Iraq" , 2nd International Conference on Ecological, Environmental and Biological Sciences (EEBS™ 2012). Oct. 13-14, Bali, Indonesia., 2012.
[7] WHO, "The control of neglected zoonotic diseases", meeting with the participation of FAO and OIE. Geneva., 2006.
[8] A. R. Satoskar, G. L. Simon, P.J. Hotez, and M. Tsuji, "Medical Parasitology, Landes Bioscience, Texas", pp.320, 2009.
https://doi.org/10.1201/9781498713672
[9] E. K. Markell, D.T. John, and W.A. Krotoski, "Medical Parasitology" 8th ed. W. B. Saunder Company. pp. 253-261, 1999.
[10] K.A. Rood, and J. Kelly, "Prevention of Hydatid Disease", Anim. Health., vol.1,pp. 1-7, 2009.
[11] L. Rinaldi, M.P. Maurelli, F. Capuano, A. G. Perugini, V. Veneziano, and S. Cringoli, "Molecular update and cystic echinococcosis in cattle and water Buffaloes of southern Italy", J. Blackwell Verlag. Zoonosis, public. Health., vol. 55, pp.119-123, 2008.
https://doi.org/10.1111/j.1863-2378.2007.01101.x
[12] L.M. Kumaratilake, and R. C. A. Thompson, "A comparison of Echinococcus granulosus from different geographical areas of Australia using secondary cyst development in mice", Int. J. Parasitol., vol.13, pp.509-515, 1983.
https://doi.org/10.1016/S0020-7519(83)80016-2
[13] A. A. Latif, A. Tanveer, A. Maqbool, N. Siddiqi, M. Kyaw-Tanner, and R. J. Traub, "Morphological and molecular characterization of Echinococcus granulosus in livestock and humans in Punjab, Pakistan", J. Vet. Parasitol., vol.170, pp. 44-49, 2010.
https://doi.org/10.1016/j.vetpar.2010.02.003
[14] E. Sanchez, O. Caceres, C. Naquira, D. Garcia, G. Patino, H. Silvia, A. C. Volotao, and O .Fernandes, "Molecular characterization of Echinococcus granulosus from Peru by sequencing of the mitochondrial cytochrome oxidase subunit 1 gene", Res. Dev. J., 105(6), pp. 806-810, 2010.
https://doi.org/10.1590/S0074-02762010000600013
[15] J. Eckert, M.A. Gemmell, F. X. Meslin, and Z. S. Pawlowski, In: "WHO/OIE Manual on Echinococcosis in Humans and Animals: A Public Health Problem of Global Concern" Paris OIE. pp. 1-265, 2001.
[16] M.F. Harandi, R.P. Hobbs, P.J. Adams, I. Mobedi, U. M. Morgan-Ryan, and R.C.A. Thompson, "Molecular and morphological characterization of Echinococcus granulosus of human and animal origin in Iran." J.Parasitol., 125, pp. 367-373. (2002).
https://doi.org/10.1017/S0031182002002172
[17] A.A. Hama, et al.," A morphologically unusual Echinococcus granulosus (G1 genotype) cyst in a cow from Kurdistan - Iraq" Special Issue: Clinical epidemiology., 5(Special Issue 2), pp.S2-5, 2015.
https://doi.org/10.4172/2161-1165.S2-00
[18] N. Magid, Prevalence of hydatid cyst among slaughter animal in Duhok province, M.Sc. Thesis, College of Veterinary Medicine, Univ. of Duhok. (2008).
[19] A. A. Hama and O. H. Shareef, "Morphological and morphometric study of Echinococcus granulosus ( metacestode ) in Sulaimani Province / Kurdistan", vol. 1, no. 1, pp. 1-6, 2016.
https://doi.org/10.24017/science.2016.1.1.6
[20] A. M. Abdullah, "Epidemiological, Comparative Enzymatic and Total Protein content of hydatid cyst of Ecchinococcus granulosus isolated from Sheep and Goats in Duhok province, Kurdistan Region of Iraq", M.Sc. Thesis, College of Education, Univ.of Duhok, 2010.
[21] H. R. Rahimi, E. B. Kia, S. H. Mirhendi, A. Talebi, H.M. Fasihi, N. Jalali-zand, and M. F. Rokni, " A new primer pair in ITS1 region for molecular studies on Echinococcus granulosus", J. Public, Health., 36 pp. 45-49, 2007.
[22] A. Daryani, R. Alaei, R. Arab, M. Sharif, M. H. Deghahan, and H. Ziaei, "Prevalence of hydatid cyst in slaughtered animals in northwest Iran", J. Anim. and Vet. Adv., vol, 5, no. 4 pp. 330-334, 2006.
[23] B. D. Ahmed, "Molecular Characterization of Echinococcus granulosus Cysts Isolated From Human and Animal Intermediate Hosts in Duhok Province, Kurdistan Region, Iraq", PhD. Thesis, College of Medicine, Univ. of Duhok, Kurdistan Region, Iraq, 2012.
[24] T. Ueno, S. Hirayama, M. Ito, E. Nishioka, Y. Fukushima, T. Satoh, M. Idei, Y. Horiuchi, H. Shoji, H. Ohmura, T. Shimizu, and T. Miida, "Albumin concentration determined by the modified bromocresol purpl method is superior to that by the bromocresol green method for assessing nutritional status in malnourished patients with inflammation", Journal Annals of Clinical Biochemistry, vol. 50 no.6, pp.576-584, 2013. [25] M. Fulks, R. L. Stout, and V. F. Dolan, '"Serum globulin predicts all-cause mortality for life insurance applicants", Journal of Insurance Medicine, vol. 44, pp.93-98, 2014. [26] I .A. Shaafie, A. H. Khan, and K. Rambabu, "Biochemical profiles of hydatid cyst fluids of E. granulosus of human and animal origin in Libya", J. Helminthol. vol.73, pp. 253-258, 1999:
https://doi.org/10.1177/0004563213480137
[27] D. P. Mcmanus, and C. N. L. Macpherson, "Strain characterization in the Hydatid organism, Echinococcus granulosus. Current status and new perspective", Ann. Trop. Med. Parasitol. vol. 78, pp. 193-198, 1984.
https://doi.org/10.1080/00034983.1984.11811799
[28] M. H. Radfar, and N. Iranyar," Biochemical profiles of hydatid cyst fluids of Echinococcus granulosus of human and animal origin in Iran Vet. Arhiv., vol. 74, pp. 435-442, 2004.
[29] Z. I. Hassan, A. A. Meerkhan, B. Boufana, A. A. Hama, B. D. Ahmed, W. M. S. Mero, S. Orsten, M. Interisano, E. Pozio, and A. Casulli, "Two haplotype clusters of Echinococcus granulosus sensu stricto in northern Iraq (Kurdistan region) support the hypothesis of a parasite cradle in the Middle East", Acta Trop., vol. 172, no. April, pp. 201-207, 2017.
https://doi.org/10.1016/j.actatropica.2017.04.028
[30] S. Kamhawi, , and N. Hijjawi, "Current studies on the epidemiology of unilocular hydatidosis in Jordan and its social implication", Report on Parasitic Diseases of the Middle East. National Institutes of Health, Bethesda, Maryland, pp. 8. 1992.
[31] M. Kouidri, F. B. Khoudja, A. Boulkaboul and S. A. Selles "Comparative Study on Fertility, Viability and Biochemical Profiles of Hydatid Cyst Fluid from the Lungs and Liver of Sheep in Algeria", World Applied Sciences Journal 31 vol.10, pp. 1699-1703, 2014.
[32] M. Refik, N. Mehmet, B. Durmaz, and M. E?ri, " Determination of some biochemical parameters in hydatid cyst fluids", Erciyes Tip Derg., vol. 24, no. 1, pp. 10-13, 2002.
Downloads
How to Cite
[1]
A. A. Hama, F. M. Ali, W. M. S. Mero, and K. hassan, “Biochemical markers and fertility rate of hydatid cyst isolated from human and animal in Sulaimani province”, KJAR, vol. 2, no. 2, pp. 1–5, Jul. 2017, doi: 10.24017/science.2017.2.2.
Article Metrics
Published
30-07-2017
Issue
Section
Pure and Applied Science
